Anaemia at admission is associated with poor clinical outcome in cerebral venous thrombosis
| Autor: | Jukka Putaala, Sini Hiltunen, Marcel Arnold, Maryam Mansour, Erik Lindgren, Jonathan M. Coutinho, Antonio Arauz, Turgut Tatlisumak, Miguel A Barboza, Katarina Jood, E Reinstra, Susanna M. Zuurbier, Mirjam Rachel Heldner, Adrien E. Groot, Suzanne M. Silvis, Masoud Ghiasian |
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| Přispěvatelé: | HUS Neurocenter, Department of Neurosciences, Neurologian yksikkö, University of Helsinki, Graduate School, ACS - Atherosclerosis & ischemic syndromes, AII - Inflammatory diseases, ANS - Neurovascular Disorders, Neurology |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Anemia 610 Medicine & health 3124 Neurology and psychiatry 03 medical and health sciences 0302 clinical medicine Modified Rankin Scale Internal medicine medicine Humans 030212 general & internal medicine Retrospective Studies Venous Thrombosis Coma anaemia business.industry 3112 Neurosciences Cancer cerebral venous thrombosis Original Articles Odds ratio Middle Aged Models Theoretical medicine.disease Thrombosis Confidence interval 3. Good health Hospitalization Venous thrombosis Neurology Female Original Article Neurology (clinical) prognosis Intracranial Thrombosis medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Silvis, Suzanne M; Reinstra, Elza; Hiltunen, Sini; Lindgren, Erik; Heldner, Mirjam R.; Mansour, Maryam; Ghiasian, Masoud; Jood, Katarina; Zuurbier, Susanna M; Groot, Adrien E; Arnold, Marcel; Barboza, Miguel A; Arauz, Antonio; Putaala, Jukka; Tatlisumak, Turgut; Coutinho, Jonathan M (2020). Anemia at admission is associated with poor clinical outcome in cerebral venous thrombosis. European journal of neurology, 27(4), pp. 716-722. Wiley 10.1111/ene.14148 European Journal of Neurology European journal of neurology. Wiley-Blackwell |
| ISSN: | 1351-5101 |
| Popis: | Background and purpose Anaemia is associated with poor clinical outcome after ischaemic and haemorrhagic stroke. The association between anaemia and outcome in patients with cerebral venous thrombosis (CVT) was examined. Methods Consecutive adult patients with CVT were included from seven centres. Anaemia at admission was scored according to World Health Organization definitions. Poor clinical outcome was defined as a modified Rankin Scale score 3-6 at last follow-up. A multiple imputation procedure was applied for handling missing data in the multivariable analysis. Using binary logistic regression analysis, adjustments were made for age, sex, cancer and centre of recruitment (model 1). In a secondary analysis, adjustments were additionally made for coma, intracerebral haemorrhage, non-haemorrhagic lesion and deep venous system thrombosis (model 2). In a sensitivity analysis, patients with cancer were excluded. Results Data for 952 patients with CVT were included, 22% of whom had anaemia at admission. Patients with anaemia more often had a history of cancer (17% vs. 7%, P |
| Databáze: | OpenAIRE |
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