Umbilical Cord Coiling in High-risk Pregnancies: Associations With Determinants of Adverse Birth Outcomes and Iron Status
| Autor: | Philip J. Katzman, Gabrielle K. Steinl, Ronnie Guillet, Yuan Ru, Elizabeth Cooper, Eva K. Pressman, Kimberly O. O'Brien, Jocelyn S. Gandelman |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Pregnancy High-Risk Umbilical cord Umbilical Cord Pathology and Forensic Medicine Young Adult 03 medical and health sciences Abnormal umbilical cord 0302 clinical medicine Pregnancy Risk Factors medicine Humans 030212 general & internal medicine 030219 obstetrics & reproductive medicine Anemia Iron-Deficiency business.industry Obstetrics Pregnancy Outcome General Medicine Iron deficiency Middle Aged medicine.disease Pregnancy Complications Fetal Diseases medicine.anatomical_structure Neonatal outcomes Pediatrics Perinatology and Child Health Etiology Female Iron status Pregnancy Multiple business |
| Zdroj: | Pediatric and Developmental Pathology. 21:537-547 |
| ISSN: | 1615-5742 1093-5266 |
| Popis: | Abnormal umbilical cord coiling has been associated with adverse neonatal outcomes, but the etiology of these findings remains poorly characterized. This study was undertaken to examine associations between cord coiling and maternal iron (Fe) status and to identify potential determinants of hypo- and hypercoiling in 2 higher risk obstetric groups: pregnant adolescents (≤18 years, n = 92) and adult women carrying twins (n = 49), triplets (n = 11), or quadruplets (n = 1). Umbilical cords were classified as hypo-, normo-, or hypercoiled using digital photographs to assess gross appearance. Hypocoiling and hypercoiling were observed in 44% (n = 86/195) and 13% (n = 26/195) of the combined study population. The prevalence of hypocoiling among women carrying multiples was over 3-fold higher than the prevalence in singleton pregnancies based on the published data. Within the entire study population, hypocoiling was associated with a lower gestational age at birth when compared to normocoiling and hypercoiling (36.3 ± 3.6 weeks [n = 86] vs 37.8 ± 2.7 [n = 83], P |
| Databáze: | OpenAIRE |
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