Some Aspects of Steroid Hormone Action
| Autor: | E S Maxwell, G M Tomkins |
|---|---|
| Rok vydání: | 1963 |
| Předmět: |
Hydrocortisone
medicine.medical_treatment Glucosephosphate Dehydrogenase Biochemistry Steroid In vivo medicine Testosterone Enzyme Inhibitors Desoxycorticosterone Diethylstilbestrol Progesterone Transaminases Adenosine Triphosphatases Pharmacology Estradiol Chemistry Mechanism (biology) Research Phosphotransferases Proteins Sex hormone receptor NAD In vitro 17-Ketosteroids Steroid hormone Metabolism Peroxidases RNA Tyrosine Steroids Amino Acid Oxidoreductases Oxidoreductases Hormone |
| Zdroj: | Annual Review of Biochemistry. 32:677-708 |
| ISSN: | 1545-4509 0066-4154 |
| DOI: | 10.1146/annurev.bi.32.070163.003333 |
| Popis: | One approach towards elucidating the mechanism of steroid hormones has been the study of steroid-enzyme interactions either in crude cell-free systems or with purified enzymes. The activities of a wide variety of enzymes are influenced by steroids, but in no case can it be stated unequivocally that the in vitro effect has an in vivo counterpart related to hormonal activity. Some of the in vitro effects may indeed have physiological significance, but until such information is available, the systems must be considered as models. As such, some have yielded important information concerning the potential modes of action of steroids at the molecular level. |
| Databáze: | OpenAIRE |
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