Immune regulation in renal inflammation
| Autor: | Katrin Neumann, Gisa Tiegs |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Histology Immune regulation animal diseases Cell 030232 urology & nephrology Renal function chemical and pharmacologic phenomena Review Kidney Pathology and Forensic Medicine Nephrotoxicity ILC2 03 medical and health sciences 0302 clinical medicine Immune system Glomerulonephritis Immune-mediated glomerulonephritis medicine Animals Humans Inflammation Innate immune system business.industry Cell Biology Regulatory T cells biochemical phenomena metabolism and nutrition medicine.disease Molecular medicine 030104 developmental biology medicine.anatomical_structure Immunology bacteria business |
| Zdroj: | Cell and Tissue Research |
| ISSN: | 1432-0878 |
| Popis: | Renal inflammation, induced by autoantigen recognition or toxic drugs, leads to renal tissue injury and decline in kidney function. Recent studies have demonstrated the crucial role for regulatory T cells in suppressing pathogenic adaptive but also innate immune responses in the inflamed kidney. However, there is also evidence for other immune cell populations with immunosuppressive function in renal inflammation. This review summarizes mechanisms of immune cell regulation in immune-mediated glomerulonephritis and acute and chronic nephrotoxicity. |
| Databáze: | OpenAIRE |
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