Skin prick test reactivity to common aeroallergens in relation to total IgE, respiratory symptoms, and smoking in a general population sample of northern Italy
| Autor: | M. Simoni, M Vellutini, Giovanni Viegi, Sapigni T, M Pedreschi, Laura Carrozzi, Paolo Paoletti, P. Biavati, P Modena, Carlo Giuntini, S. Baldacci |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Allergy medicine.medical_specialty Skin prick test Adolescent Immunology Population Prevalence Immunoglobulin E medicine.disease_cause Airborne allergen Atopy Allergen Sex Factors Internal medicine Smoking total IgE Immunology and Allergy Medicine Humans Respiratory symptoms education Child Asthma Aged Skin Tests education.field_of_study General population Age Factors Allergens Cross-Sectional Studies Female Middle Aged Smoking biology business.industry medicine.disease biology.protein business |
| Zdroj: | Allergy. 51(3) |
| ISSN: | 0105-4538 |
| Popis: | Skin prick test (SPT) reactivity to common airborne allergens and its relationships to sex, age, smoking habits, and respiratory symptoms/ diseases were evaluated in a general population sample (n= 2841, 8–75 years of age) living in the Po delta area (northern Italy). Subjects completed a standardized questionnaire and underwent prick tests (12 local allergens, a negative and a positive control) and determination of total serum IgE. Atopy was evaluated by measuring the maximal diameter for each allergen, after subtracting that of the negative control. Thirty-one percent of subjects showed a positive skin response at a 3-mm threshold. Pollens, Dermatophagoides pteronyssinus, and D. farinae caused the highest frequencies of reactions. Young people and those who had never smoked had higher prevalence rates of SPT reactivity. Asthma, asthma symptoms, and rhinitis were significantly associated with SPT reactivity in both sexes (cough only in females) and with the number of positive reactions. IgE values were also significantly associated with SPT reactivity. In conclusion, our findings indicate that almost one-third of the general population of an Italian rural area is skin test positive, emphasizing the importance of assessing atopy in respiratory epidemiologic surveys. |
| Databáze: | OpenAIRE |
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