All‐Aqueous, Surfactant‐Free, and pH‐Driven Nanoformulation Methods of Dual‐Responsive Polymer Nanoparticles and their Potential use as Nanocarriers of pH‐Sensitive Drugs

Autor:	Víctor D. Lechuga‐Islas, Melisa Trejo‐Maldonado, Ilya Anufriev, Ivo Nischang, İpek Terzioğlu, Jens Ulbrich, Ramiro Guerrero‐Santos, Luis E. Elizalde‐Herrera, Ulrich S. Schubert, Carlos Guerrero‐Sánchez
Rok vydání:	2023
Předmět:	Biomaterials Polymers and Plastics Materials Chemistry Bioengineering Biotechnology
Zdroj:	Macromolecular Bioscience. 23:2370002
ISSN:	1616-5195 1616-5187
Popis:	All-aqueous, surfactant-free, and pH-driven nanoformulation methods to generate pH- and temperature-responsive polymer nanoparticles (NPs) are described. Copolymers comprising a poly(methyl methacrylate) (PMMA) backbone with a few units of 2-(dimethylamino)ethyl methacrylate (DMAEMA) are solubilized in acidic buffer (pH 2.0) to produce pH-sensitive NPs. Copolymers of different molar mass (2.3-11.5 kg mol
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68da93fab1206f2f90c7514afa7b80d https://doi.org/10.1002/mabi.202370002 Zobrazit plný text záznamu Plný text