Generation and Measurement of Chlorine Dioxide Gas at Extremely Low Concentrations in a Living Room: Implications for Preventing Airborne Microbial Infectious Diseases
| Autor: | Takashi Shibata, Koushirou Sogawa, Yasuhiro Takigawa, Norio Ogata |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Pharmacology Chlorine dioxide Chromatography Gas Chemistry Ion chromatography Parts-per notation Oxides General Medicine Gas concentration Living room Environment Controlled Gas analyzer 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology Environmental chemistry Animals Particulate Matter Chlorine Compounds Gas generator Respiratory Tract Infections Volume concentration |
| Zdroj: | Pharmacology. 99(3-4) |
| ISSN: | 1423-0313 |
| Popis: | Background/Aims: Preventing respiratory diseases caused by airborne microbes in enclosed spaces is still not satisfactorily controlled. At extremely low concentrations (about 30 parts per billion), chlorine dioxide (ClO2) gas can inactivate airborne microbes and prevent respiratory disease. It has no toxic effect on animals at this level. However, controversies still remain regarding how to measure concentrations of ClO2 gas at such low levels. It is therefore necessary to prove that measured gas concentrations are accurate and reproducible. Methods: ClO2 gas was released from a gas generator and its concentration was measured by a novel highly sensitive gas analyzer. We compared its data with those from ion chromatography. Results: We demonstrate that the gas concentrations measured in a room using the gas analyzer are accurate and reproducible after comparing the results with those from ion chromatography. However, the temperature dependence of the gas analyzer was found. Therefore, data correction is required for each temperature at which gas concentration is measured. A theoretical analysis of the gas concentrations predicted by the rate of ClO2 gas released from the ClO2 generator was also performed. Conclusion: Our results advance progress toward using low concentration ClO2 gas to prevent airborne infectious diseases such as influenza. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|