The study of early application with Dixiong Decoction (地芎汤) for non-small cell lung cancer to decrease the incidence and severity of radiation pneumonitis: A prospective, randomized clinical trial
| Autor: | Ming-hui Yang, Chun Xiao, Yong-qi Dou, Xu-hui Yang, Zheng-mao Wei |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Lung Neoplasms medicine.medical_treatment Decoction Gastroenterology law.invention Randomized controlled trial Adrenal Cortex Hormones law Carcinoma Non-Small-Cell Lung Internal medicine medicine Humans Pharmacology (medical) Prospective Studies Prospective cohort study Lung cancer Pneumonitis Radiotherapy business.industry Incidence Incidence (epidemiology) Pneumonia General Medicine medicine.disease Clinical trial Radiation therapy Complementary and alternative medicine Physical therapy business |
| Zdroj: | Chinese Journal of Integrative Medicine. 16:411-416 |
| ISSN: | 1993-0402 1672-0415 |
| DOI: | 10.1007/s11655-010-9998-x |
| Popis: | To evaluate the efficacy of compound Dixiong Decoction (地芎汤, a Chinese herbal decoction) on early prevention of radiation pneumonitis. Forty-six patients with non-small cell lung cancer who were planning to receive radiotherapy were randomly assigned to the treatment group treated with the compound Dixiong Decoction and the control group treated with a commonly used herbal decoction which has the effects of supplementing qi and nourishing yin, clearing heat and detoxifying at the time of radiotherapy. Primary measure was the incidence of radiation pneumonitis after radiotherapy. Secondary outcomes included Watters clinical radiographic physiologic (CRP) dyspnea score, the Radiation Therapy Oncology Group (RTOG) grading score, Karnofsky Performance Status (KPS) score, and the application of corticosteroids. The incidence of radiation pneumonitis in the treatment group was 10.0%, while that in the control group was 26.3% (P=0.0032). The Watters CRP dyspnea score and RTOG grading score in the treatment group were significantly =lower than those in the control group (P |
| Databáze: | OpenAIRE |
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