Prospective Evaluation of Floppy Eyelid Syndrome at Baseline and after CPAP Therapy

Autor: Fausto Carvalheira, Maria J. Silva, Nádia Lopes, João Paulo Castro Sousa, Cláudia Moreira, Maria J Vieira
Rok vydání: 2020
Předmět:
Zdroj: Current Eye Research. 46:31-34
ISSN: 1460-2202
0271-3683
DOI: 10.1080/02713683.2020.1776332
Popis: Floppy eyelid syndrome (FES) is an ocular manifestation of obstructive sleep apnea (OSA), but no studies have analyzed whether it can be improved by nocturnal continuous positive airway pressure (CPAP) therapy. The aim of this study was to analyze the effect of CPAP on FES by comparing objective measurements before and after 6 months of CPAP therapy.We conducted a prospective study of 47 patients (74.5% males) with newly diagnosed OSA at a secondary care Portuguese hospital who underwent objective diagnostic testing for FES (upper eyelid eversion for6 seconds and tarsal conjunctival exposure and upper eyelid laxity ≥1.5 mm). Patients with hyperelastic eyelid or FES were re-evaluated by the same ophthalmologist (blinded to the patients' condition) after 6 months of CPAP therapy.Mean apnea hypopnea index (AHI), analyzed as number of events per hour, was 28.7 ± 18.6 overall and 42.8 ± 20.0 in the supine position. Thirty-four percent of patients had FES. Mean AHI in the supine position was significantly higher in patients with FES (A higher AHI in the supine position may be predictive of FES. CPAP therapy might reverse FES and patients with non-reversible FES appear to have more severe OSA and a worse airway access.
Databáze: OpenAIRE