Effectiveness Oral Theophylline, Piracetam, and Iron Treatments in Children With Simple Breath-Holding Spells
| Autor: | Alper I. Dai, Abdullah T. Demiryürek |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Anemia Iron Breath Holding 03 medical and health sciences 0302 clinical medicine Theophylline Seizures 030225 pediatrics BREATH-HOLDING SPELLS medicine Humans Retrospective Studies business.industry Piracetam Retrospective cohort study medicine.disease Treatment Outcome Iron-deficiency anemia Anesthesia Child Preschool Pediatrics Perinatology and Child Health Female Neurology (clinical) business 030217 neurology & neurosurgery Iron therapy medicine.drug |
| Zdroj: | Journal of child neurology. 35(1) |
| ISSN: | 1708-8283 |
| Popis: | Breath-holding spells (BHS) are common nonepileptic paroxysmal events in children. This is a retrospective study to compare the effectiveness of oral theophylline, piracetam, and iron treatments in children with simple BHS. A total of 146 children (75 girls and 71 boys) with simple BHS were included to this retrospective study. Children were divided into 4 groups: nontreated (no anemia and no treatment), oral theophylline (10 mg/kg/d as a single daily dose), piracetam (40 mg/kg/d in 2 divided doses), and elementary iron (3 mg/kg/d as a single daily dose) treatments. Iron therapy had been given only in children with iron deficiency anemia. Neurologic, cardiologic, and biochemical evaluations were performed for all children. The majority of the patients had cyanotic spells (83.6%). The frequency of attacks/month was markedly decreased with iron (58.8%) and theophylline (82.9%) treatments, but not with piracetam therapy (8.8%) and nontreated group (4.7%). Satisfaction of the parents/caregivers was found to be high in the theophylline group ( P < .001). Our results showed that theophylline was the most effective therapy to decrease the frequency of simple BHS in children. |
| Databáze: | OpenAIRE |
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