The Role of Myocardial Perfusion Gated SPECT Study in Women with Coronary Artery Disease: A Correlative Study
| Autor: | Mustafa Kilic, Erdal Nihat Akalin, Fatma Suna Kiraç, Doğangün Yüksel, Olga Yaylali |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty congenital hereditary and neonatal diseases and abnormalities Myocardial ischemia lcsh:R895-920 Gated SPECT lcsh:Medicine metabolic syndrome Coronary artery disease Myocardial perfusion imaging Internal medicine Atherosclerosis myocardial perfusion imaging Metabolic Syndrome medicine Radiology Nuclear Medicine and imaging lcsh:R5-920 medicine.diagnostic_test business.industry lcsh:R medicine.disease Surgery Coronary arteries Invasive coronary angiography medicine.anatomical_structure Cardiology Original Article Metabolic syndrome lcsh:Medicine (General) business Perfusion coronary artery disease |
| Zdroj: | Molecular Imaging and Radionuclide Therapy Molecular Imaging and Radionuclide Therapy, Vol 21, Iss 2, Pp 69-74 (2012) |
| ISSN: | 2147-1959 2146-1414 |
| Popis: | Objective: We aimed to evaluate the role of gated myocardial perfusion SPECT (MPS) and to investigate whether only the invasive coronary angiography (CAG) is sufficient in the diagnosis of the coronary artery disease (CAD) in women. Material and Methods: Sixty-four women (62 +/- 10 years) with known CAD were included in this study. They had echocardiography (ECHO), stress/rest gated MPS and invasive CAG. Coronary stenosis as of > 50 % in invasive CAG was accepted as significant. Gated MPS data were compared with invasive CAG and ECHO. Results: Invasive CAG results were abnormal in 34 patients, and normal in 30 cases. Myocardial ischemia was detected by gated MPS in 22/30 cases with normal invasive CAG, 6 had mild coronary stenosis in major coronary arteries ranging from 30% to 50% in invasive CAG. 16/22 women were diagnosed as metabolic syndrome according to MetSend Diagnostic Criteria and only 8 of 30 patients with normal invasive CAG had false positive MPS data on the reevaluation by a nuclear cardiologist. Conclusion: We think that invasive coronary angiography method is not sufficient alone in the diagnosis of CAD in women. Gated MPS study is recommended to achieve the final decision for myocardial ischemia in the cases with CAD and raw data must always be evaluated to avoid attenuation artifacts. |
| Databáze: | OpenAIRE |
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