Efficacy and Safety of Blood Flow Restriction Training in Patients With Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Autor: Guo-Xin Ni, Lin Cheng, Wei Li, Hao-Nan Wang, Yan Chen, Yi-Hui Cai
Rok vydání: 2021
Předmět:
Zdroj: Arthritis careresearchREFERENCES. 74(1)
ISSN: 2151-4658
Popis: OBJECTIVE To evaluate the efficacy and safety of blood flow restriction training (BFRT) in the treatment of patients with knee osteoarthritis (KOA). METHOD Seven electronic databases were searched to identify trials comparing BFRT and conventional resistance training (RT) in a population with KOA. Studies were selected according to the inclusion and exclusion criteria. Standardized mean differences (SMDs) or risk ratio (RR) with 95% confidence intervals (CIs) was calculated to compare outcome measures of the groups. The methodological quality of selected studies and the quality of evidence were evaluated for included studies. RESULTS A total of five studies were included in this meta-analysis, with very low to moderate risk of bias. The pooled results showed no significant difference between BFRT and conventional RT for KOA, including pain (SMD = -0.04 [95%CI: -0.31, 0.24], P = 0.79), physical function performance (SMD = 0.12 [95%CI: -0.55, 0.78], P = 0.73), self-reported function (SMD = 0.14 [95%CI: -0.24, 0.52], P = 0.48), and AEs (RR = 0.45 [95%CI: 0.20, 1.01], P = 0.05). In subgroup analysis, BFRT had a lower incidence of adverse events when compared with high-load resistance training (HLRT). CONCLUSION Data from pooled studies showed BFRT may not have greater efficacy for treating patients with KOA and it is less likely to have a higher risk of adverse events. However, limited evidence supports that BFRT is likely safer than the HLRT. More evidence with high quality is needed in further research for its efficacy and safety.
Databáze: OpenAIRE
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