Evaluation of the Coating with TiO2 Nanoparticles as an Option for the Improvement of the Characteristics of NiTi Archwires: Histopathological, Cytotoxic, and Genotoxic Evidence
| Autor: | Rubén Daniel Arellano Pérez-Vertti, Roberto Beltrán del Río-Parra, José Alfredo Facio Umaña, Nadia Denys Betancourt-Martínez, Rubén García-Garza, J. Jiménez-Villarreal, Javier Morán-Martínez, Lydia Enith Nava-Rivera, María Soñadora Niño-Castañeda, Pilar Carranza-Rosales |
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| Rok vydání: | 2018 |
| Předmět: |
Necrosis
Materials science Article Subject Biocompatibility 02 engineering and technology engineering.material medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Coating lcsh:Technology (General) medicine Cytotoxic T cell General Materials Science Viability assay Cytotoxicity technology industry and agriculture 030206 dentistry 021001 nanoscience & nanotechnology Nickel titanium engineering lcsh:T1-995 medicine.symptom 0210 nano-technology Genotoxicity Biomedical engineering |
| Zdroj: | Journal of Nanomaterials, Vol 2018 (2018) |
| ISSN: | 1687-4129 1687-4110 |
| Popis: | For the EPD, different voltages and different times were used. Male rats were used in four groups (n=3) with different treatments. The blood sample was obtained for genotoxic analysis and liver and kidney organs were removed for histopathological analysis. The amount of NPs TiO2 deposited on the samples of the arches increases gradually in the times of 15 and 30 s. At all voltages, however, at 45, 60, 75, and 90 s, there is an increase up to 25 V. Cell viability in lymphocytes treated with TiO2 NPs did not cause genotoxicity. In the histopathological findings of hepatic and renal tissue, nuclear alterations and necrosis were observed. The objective of the study was to improve the physical and biocompatibility characteristics of the NiTi arches for which the EPD is used. The technique for the deposition of TiO2 NPs was used, where this technique could be used as an economical and versatile way to perform homogeneous depositions even on surfaces with the complexity of the NiTi alloy. As for genotoxicity and cytotoxicity, we continue to have controversial results. |
| Databáze: | OpenAIRE |
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