DOT-ELISA and parasitological examination for diagnosis of Schistosoma mansoni infection in Nigeria
Autor: | C. J. Uneke, M. O. Njoku, G. Chuga, H. B. Mafuyai |
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Jazyk: | angličtina |
Rok vydání: | 2006 |
Předmět: |
medicine.medical_specialty
Medicine (General) diagnosis Agriculture (General) prevalence Serology S1-972 Medical microbiology R5-920 Internal medicine parasitic diseases Epidemiology medicine biology Public health Significant difference biology.organism_classification infection Parasitology dot-elisa Immunology Dot elisa Animal Science and Zoology Schistosoma mansoni schistosoma mansoni |
Zdroj: | Helminthologia, Vol 43, Iss 1, Pp 11-15 (2006) |
ISSN: | 1336-9083 0440-6605 |
Popis: | Schistosoma mansoni infection constitutes significant economic and public health consequences. Accurate diagnosis of the infection is imperative in order to identify subjects needing care in the broadest sense. In this study the dot-ELISA and direct parasitological method were compared in the diagnosis of S. mansoni infection in Jos, Nigeria. Of the 106 subjects studied 64.2 % were S. mansoni positive serologically while only 10.4 % of them were found to have the parasite’s egg in their stools. Individuals aged 20–29 years of both sexes had highest prevalence of 73.9 % and 21.7% by serological and parasitological diagnosis respectively. Prevalence of infection among males was 13.5 % and 7.4 % among females by parasitology. By serology the corresponding figures were 59.6 % and 68.5 % respectively. No significant difference was observed by parasitology (χ2=4.534, P ≤ 0.05) and by serology (χ2=2.00, P ≤ 0.05). Results advocate for serodiagnostic technique over parasitological method in S. mansoni surveillance and epidemiological studies. |
Databáze: | OpenAIRE |
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