Raccoons (Procyon lotor) in the Madrid region of Spain are carriers of antimicrobial-resistant Escherichia coli and enteropathogenic E. coli
| Autor: | Abel Martínez-Rodrigo, Ricardo de la Fuente, José A. Orden, Javier Carrión, Alicia Mas, Jorge Blanco, Saskia C. Flament-Simon, Gustavo Domínguez-Bernal, Francisco Sobrino, Isidro García-Meniño |
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| Přispěvatelé: | Comunidad de Madrid, Instituto de Salud Carlos III, Xunta de Galicia, Ministerio de Educación, Cultura y Deporte (España) |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Epidemiology Tetracycline 030231 tropical medicine 030106 microbiology Enteropathogenic E. coli Biology medicine.disease_cause Antimicrobial resistance Microbiology 03 medical and health sciences Enteropathogenic Escherichia coli Feces 0302 clinical medicine Antibiotic resistance Ampicillin Zoonoses Drug Resistance Bacterial parasitic diseases medicine Escherichia coli Animals Disease Reservoirs General Veterinary General Immunology and Microbiology Shiga-Toxigenic Escherichia coli Public Health Environmental and Occupational Health Antimicrobial Anti-Bacterial Agents Infectious Diseases Streptomycin VTEC Spain Carrier State Verotoxinproducing E. coli Raccoons medicine.drug |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | The role of wildlife in the epidemiology of antimicrobial resistance is unclear. Raccoons in North America can carry a variety of enteric bacteria, with associated antimicrobial resistance, that could infect humans and livestock. The potential for raccoons to carry these bacteria in Europe, where they are an invasive species, has not been explored. Our objectives were to determine the prevalence of Escherichia coli with associated antimicrobial resistance in raccoons from the Madrid region of Spain and to determine whether they are carriers of potential human pathogens, including verotoxin-producing E. coli (VTEC) and enteropathogenic E. coli (EPEC). In total, we tested 237 E. coli isolates from the faeces of 83 euthanized raccoons for susceptibility to 14 antimicrobial agents and the presence of VTEC and EPEC. Antimicrobial resistance to at least one antimicrobial was detected in the faeces of 51% (42/83; 95% CI, 40.1–61.1) of the raccoons tested. A high percentage of raccoons carried, in their faeces, E. coli isolates resistant to ampicillin (33%), streptomycin (33%), tetracycline (30%), sulphafurazole (31%) and trimethoprim-sulphamethoxazole (23%). We detected one isolate of extended-spectrum β-lactamase-producing E. coli from the faeces of one raccoon. We detected VTEC in the faeces of one raccoon, and EPEC in the faeces of 12% (10/83) of the raccoons. Of the raccoons that carried EPEC in their faeces, 60% (6/10) carried EPEC isolates that exhibited characteristics associated with pathogenicity in humans. Raccoons in Madrid can carry pathogenic and antimicrobial-resistant E. coli in their faeces and may be a risk to public health because of their potential to contaminate food and the environment with their faeces. Comunidad de Madrid (Spain), PI16/01477 from Plan Estatal de I+D+I 2013-2016, Instituto de Salud Carlos III (ISCIII), Subdirección General de Evaluación y Fomento de la Investigación and Fondo Europeo de Desarrollo Regional (FEDER), and ED431C2017/57 from the Consellería de Cultura, Educación e Ordenación Universitaria (Xunta de Galicia) and FEDER; Spanish Ministerio de Educación, Cultura y Deporte |
| Databáze: | OpenAIRE |
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