Predicting Successful Recanalization in Patients with Native Coronary Chronic Total Occlusion: The Busan CTO Score

Autor: Moo Hyun Kim, Kwang Min Lee, Young Rak Cho, Tae Hyung Kim, Soo Jin Kim, Cai De Jin, Victor L. Serebruany
Rok vydání: 2017
Předmět:
Male
medicine.medical_specialty
Multivariate analysis
Cross-sectional study
medicine.medical_treatment
Dentistry
030204 cardiovascular system & hematology
Severity of Illness Index
03 medical and health sciences
Coronary circulation
Percutaneous Coronary Intervention
0302 clinical medicine
Japan
Predictive Value of Tests
Coronary Circulation
Internal medicine
Severity of illness
medicine
Humans
Pharmacology (medical)
Prospective Studies
Registries
030212 general & internal medicine
Prospective cohort study
Aged
business.industry
Percutaneous coronary intervention
Middle Aged
Coronary Vessels
Cross-Sectional Studies
Logistic Models
Treatment Outcome
medicine.anatomical_structure
Coronary Occlusion
ROC Curve
Coronary occlusion
Predictive value of tests
Multivariate Analysis
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
Zdroj: Cardiology. 137:83-91
ISSN: 1421-9751
0008-6312
Popis: Background: The optimal strategy to manage chronic total occlusion (CTO) remains unclear. The Japanese CTO multicenter registry (J-CTO) score is an established tool for predicting successful recanalization. However, it does not take into account nonangiographic predictors for final technique success. In the present study, we designed and tested a scoring model called the Busan single-center CTO registry (B-CTO) score combining clinical and angiographic characteristics to predict successful CTO recanalization in Korean patients. Methods: Prospectively enrolled CTO patients (n = 438) undergoing coronary intervention (1999-2015) were assessed. The B-CTO score comprises 6 independent predictors: age 60-74 years and lesion length ≥20 mm were assigned 1 point each, while age ≥75 years, female gender, lesion location in the right coronary artery, blunt stump, and bending >45° were assigned 2 points each. For each predictor, the points assigned were based on the associated odds ratio by multivariate analysis. The lesions were classified into 4 groups according to the summation of points scored to assess the probability of successful CTO recanalization: easy (score 0-1), intermediate (score 2-3), difficult (score 4-5), and very difficult (score ≥6). CTO opening was designated as the primary endpoint regardless of the interventional era or the skill of the operator. Results: The final success rate for B-CTO was 81.1%. The probability of successful recanalization for patient groups classified as easy (n = 64), intermediate (n = 148), difficult (n = 134), and very difficult (n = 92) was 95.3, 86.5, 79.1 and 65.2%, respectively (p for trend Conclusions: The B-CTO score has been designed and validated in Korean patients with native coronary CTO and is an improved tool for predicting successful recanalization. Wider application of the B-CTO score remains to be explored.
Databáze: OpenAIRE