The Efficacy of Botulinum Toxin in Patients with Cervicogenic Headache: a Placebo-Controlled Clinical Trial
| Autor: | Yasar Kutukcu, Bilgin Öztürk, Zeki Odabasi, Ömer Karadaş, Ümit Hıdır Ulaş |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Visual analogue scale medicine.medical_treatment lcsh:Medicine Placebo Placebo group Health Care Sciences and Services Cervicogenic headache medicine In patient Sağlık Bilimleri ve Hizmetleri Botulinum toxin A Saline business.industry lcsh:R General Medicine Cervicogenic headache Botulinum toxin A medicine.disease Botulinum toxin Surgery Clinical trial Anesthesia Original Article business medicine.drug |
| Zdroj: | Balkan Medical Journal, Vol 29, Iss 2, Pp 184-187 (2012) Volume: 2012, Issue: 2 184-187 Balkan Medical Journal |
| ISSN: | 2146-3131 2146-3123 |
| Popis: | Objective: Botulinum toxin type-A (BoNTA) has been considered a treatment option for CH. The aim of this study was to assess the effectiveness of BoNTA treatment in patients with medically resistant CH. Materials and Methods: Forty patients with CH were included in the study. Patients in the BoNTA group (n=20) were administered 10 U of BoNTA bilaterally to the frontal muscles, 20 U to the temporal muscles, 15 U to the semispinalis capitis, 15 U to the splenius capitis, and 15 U to the trapezius muscles (total: 150 U). Patients in the placebo group (n=20) received 0.2 mL of saline administrated to the same sites. All participations were evaluated 6 and 12 weeks after treatment; side effects, the number of painful days, severity (by visual analogue scale, VAS) and frequency of pain were evaluated. Results: In the BoNTA group, the severity and frequency of pain 6 and 12 weeks post treatment were significantly lower than pre-treatment levels (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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