Iranian Registry of Infective Endocarditis (IRIE): Time to relook at the guideline, regarding to regional differences
| Autor: | Feridoun Noohi, Azin Alizadehasl, Nasim Naderi, Monireh Kamali, Leila Rezvani, Majid Kyavar, Anita Sadeghpour, Hamidreza Pasha, Massoud Movassaghi, Mohammad Mahdi Peighambari, Shabnam Boudagh, Majid Maleki, Hooman Bakhshandeh, Alireza Alizadeh Ghavidel, Behshid Ghadrdoost |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system Population 030204 cardiovascular system & hematology medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Internal medicine Mitral valve Epidemiology medicine Mitral valve prolapse 030212 general & internal medicine education education.field_of_study Original Paper business.industry Guideline medicine.disease medicine.anatomical_structure Staphylococcus aureus lcsh:RC666-701 Infective endocarditis Cardiology and Cardiovascular Medicine business Regional differences |
| Zdroj: | International Journal of Cardiology. Heart & Vasculature International Journal of Cardiology: Heart & Vasculature, Vol 26, Iss, Pp-(2020) |
| ISSN: | 2352-9067 |
| Popis: | Aims Infective endocarditis (IE) remained a potentially fatal disease with high rate of mortality and morbidity. The epidemiology and global burden of IE are largely different between the countries. We aimed to address the epidemiological aspects of IE in a tertiary hospital in Tehran, Iran. Methods and Results Between 2006–2018, all adults patients with diagnosis of IE were enrolled in the Iranian Registry of Infective Endocarditis (IRIE). The data were analyzed using the χ2, Kolmogorov–Smirnov, and Mann–Whitney U tests. Overall, 602 patients, 407 (67.6%) men, mean age 46 ± 16 years were recruited. Positive blood culture found in 49%.The most common underlying heart diseases were: Congenital heart diseases (CHD) particularly bicuspid aortic valves (BAV) and ventricular septal defects (VSD) in 37%, followed by degenerative heart diseases :flail and mitral valve prolapse (16.3%), intravenous drug user in 12.6%, prosthetic valves in 11.1%, previous IE (8.9%), rheumatic heart diseases (RHD) in 8.4%. The most causative microorganisms were Staphylococcus aureus, Enterococci, coagulase-negative staphylococci and Streptococcus viridans. Cardiac or extra cardiac complications occurred in 56.6% of the patients. Conclusions Based on IRIE, IE occurs in the younger population in Iran with high rates of blood culture-negative IE. RHD are not the main cause of IE in Iran, CHD including BAV and VSDs, followed by prolaptic or flail mitral valve were the most common. These 2 groups can be considered a high-risk group for IE. More than half of the patients with IE had cardiac or extra cardiac complications. |
| Databáze: | OpenAIRE |
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