Incidence of acute kidney injury in the neonatal intensive care unit
| Autor: | Mohamed M Shehab, Mohamed Abd-Elrheem, Doaa Mohammed Youssef, Hadeel M. Abdelrahman |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Heart Defects
Congenital Male medicine.medical_specialty Neonatal intensive care unit Oliguria lcsh:Medicine Polycythemia urologic and male genital diseases Urine sodium Sepsis Sex Factors Risk Factors Internal medicine Intensive Care Units Neonatal medicine Humans Prospective Studies Asphyxia Asphyxia Neonatorum Hematoma Respiratory Distress Syndrome Newborn medicine.diagnostic_test Respiratory distress Dehydration business.industry Incidence lcsh:R Acute kidney injury Infant Newborn Complete blood count General Medicine Acute Kidney Injury medicine.disease Respiration Artificial female genital diseases and pregnancy complications Surgery Egypt Female medicine.symptom business |
| Zdroj: | Saudi Journal of Kidney Diseases and Transplantation, Vol 26, Iss 1, Pp 67-72 (2015) |
| ISSN: | 1319-2442 |
| Popis: | The aim of this work is to study the incidence of acute kidney injury (AKI) in neonates admitted to the neonatal intensive care unit (NICU) over a six-month period from September 2011 to March 2012. This prospective study was performed on 250 neonates admitted to the NICU at the Children's Hospital, Faculty of Medicine, Zagazig University. All neonates were subjected to detailed history taking, including pre-natal, natal and post-natal history, with stress on symptoms suggestive of AKI. All neonates were examined thoroughly and the following investigations were performed: Blood urea nitrogen (BUN), serum creatinine, sodium, potassium, calcium, complete blood count, C-reactive protein, arterial blood gases, urine sodium and urine creatinine. AKI was diagnosed in 27 cases (10.8%), including 12 females and 15 males. 40.7% of the AKI cases were born after full-term pregnancy while 59.3% were pre-term babies. 29.6% of the AKI cases had oliguria, and there was male sex predominance, with a male-female ratio of 1.3:1. The cause of AKI was pre-renal in 96.3% and intrinsic renal in 3.7% of the cases. The predisposing factors for AKI were sepsis in 63% of the cases, respiratory distress syndrome in 55.6%, mechanical ventilation in 51.9%, peri-natal asphyxia in 18.5%, dehydration in 14.8%, surgical operation in 11.1%, congenital heart disease in 7.4%, sub-galeal hematoma in 3.7%, polycythemia in 3.7% and intra-ventricular hemorrhage in 3.7% of the cases. Our data suggest that pre-renal failure was the most common form of AKI in our patients. Early recognition of risk factors such as sepsis, peri-natal asphyxia or peri-operative problems and rapid effective treatment of contributing conditions will reduce the incidence of AKI in the neonatal period. |
| Databáze: | OpenAIRE |
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