Factors influencing the prescribed dose of opioid analgesics in cancer patients
| Autor: | Chikako Numata, Ikuko Tanaka, Kazuki Aogaki, Yoshiaki Okamoto, Ryouhei Ishii, Yoshinobu Matsuda, Momoyo Hashimoto, K. Moriwaki |
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| Rok vydání: | 2020 |
| Předmět: |
Palliative care
Analgesic 03 medical and health sciences Route of administration 0302 clinical medicine 030202 anesthesiology Oral administration Neoplasms medicine Humans Blood test Pharmacology (medical) Practice Patterns Physicians' Aged Analgesics Morphine medicine.diagnostic_test business.industry Cancer Pain General Medicine Middle Aged Analgesics Opioid Anesthesiology and Pain Medicine Anesthesia Liver function Cancer pain business medicine.drug |
| Zdroj: | Journal of Opioid Management. 16:247-252 |
| ISSN: | 1551-7489 |
| DOI: | 10.5055/jom.2020.0578 |
| Popis: | The dose of opioids prescribed for cancer pain does not always correlate with the actual pain severity. However, there is little evidence to explain this observation. In the present study, we sought to determine factors that influence the dose of opioid analgesics. A total of 227 patients who were administered opioids between August 2012 and May 2016 and later expired within the Department of Palliative Care at Ashiya Municipal Hospital were included, and the following variables were examined: age, sex, type of cancer, Verbal Rating Scale before and after the administration of the maximum prescribed dose of opioids, type of opioids and route of administration, blood test results, pain severity, and use of adjuvants. Data were analyzed using step-wise multiple linear regression. Median of the maximum prescribed dose of opioids, expressed in oral morphine equivalent, was 68.6, 60.0, and 39.2 mg for patients aged |
| Databáze: | OpenAIRE |
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