Detection of an Intrathymic Parathyroid Adenoma by Tc-99m Tetrofosmin

Autor: Alessandro Giordano, Paola Pasquini, G Meduri, Salvatore Maria Corsello
Rok vydání: 1996
Předmět:
Zdroj: Clinical Nuclear Medicine. 21:996-998
ISSN: 0363-9762
DOI: 10.1097/00003072-199612000-00027
Popis: A 35-year-old woman who had hyperparathyroidism (increased serum levels of calcium and parathormone) and normal neck US scan, underwent standard Tl-201/ Tc-99m pertechnetate parathyroid scintigraphy with the addition of early and delayed imaging with Tc-99m tetrofosmin. A rounded area of increased uptake of Tl-201 and Tc-99m tetrofosmin, located in the upper left mediastinum, was detectable on raw and Tc-99m subtracted images, which represented an ectopic parathyroid adenoma that was surgically removed and histologically confirmed as an intrathymic parathyroid adenoma. Adenoma detectability was much better with Tc-99m tetrofosmin than with Tl-201 as shown by the higher tumor to background ratio. Such favorable imaging characteristics suggest that Tc-99m tetrofosmin may have the potential to act as a suitable agent for parathyroid scintigraphy.
Databáze: OpenAIRE