Mechanisms of Resistance to Antimicrobial Drugs in Pathogenic Gram-Positive Cocci
| Autor: | Slawomir Majewski, Grażyna Młynarczyk, M. Kmera-Muszynska, Andrzej Młynarczyk, B. Mlynarczyk |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.drug_class
Antibiotics Drug resistance Tigecycline Biology Microbiology chemistry.chemical_compound Drug Resistance Bacterial Drug Discovery polycyclic compounds medicine Gram-Positive Cocci Pharmacology General Medicine biochemical phenomena metabolism and nutrition bacterial infections and mycoses Antimicrobial Virology Anti-Bacterial Agents chemistry RNA Ribosomal Protein Biosynthesis Linezolid Iclaprim bacteria Daptomycin medicine.drug |
| Zdroj: | Mini-Reviews in Medicinal Chemistry. 10:928-937 |
| ISSN: | 1389-5575 |
| DOI: | 10.2174/138955710792007204 |
| Popis: | Many species of Gram-positive cocci are pathogenic. The most important are staphylococci, streptococci, and enterococci. Widespread usage of antibiotics was the main cause for the appearance and spread of resistance to almost all antimicrobials. The occurrence, mechanisms, and genetic background of resistance to antimicrobial drugs other than beta-lactams and glycopeptides among pathogenic staphylococci, streptococci, and enterococci are discussed in the text. Well-established agents (such as macrolides, lincosamides, streptogramins, aminoglycosides, quinolones, mupirocin, chloramphenicol) as well as new agents (linezolid, daptomycin, quinupristine/dalfopristine, ratapamulin, tigecycline, iclaprim and new generations of quinolones) are considered. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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