Identification and in vitro antioxidant activities of phenolic compounds isolated from Cynoglossum cheirifolium L
| Autor: | Beddou Fawzia, Belarbi Karima, Bensaid Ilhem, Bekhechi Chahrazed, El Haci Imad Abdelhamid, Atik Bekkara Fawzia |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
DPPH
Drug Evaluation Preclinical Plant Science 01 natural sciences Biochemistry Depsides p-Coumaric acid Antioxidants Analytical Chemistry Ferulic acid chemistry.chemical_compound Phenols Gallic Acid Caffeic acid Organic chemistry Food science Gallic acid Chromatography High Pressure Liquid Flavonoids 010405 organic chemistry Plant Extracts Rosmarinic acid Organic Chemistry food and beverages Syringic acid Boraginaceae 0104 chemical sciences Plant Leaves 010404 medicinal & biomolecular chemistry chemistry Cinnamates |
| Zdroj: | Natural product research. 32(4) |
| ISSN: | 1478-6427 |
| Popis: | In an extensive search for bioactive compounds from plant sources, the quantitative and qualitative characterisation of the compounds present in Cynoglossum cheirifolium extracts was studied. Total phenolic and flavonoid contents were determined by spectrophotometric techniques. In vitro antioxidant and radical scavenging profiling was determined through DPPH• scavenging activity and Ferric reducing antioxidant power (FRAP). Our study showed that leaves produce more phenolic compounds, followed by flowering aerial part. The butanolic fraction obtained from leaves extract exhibited the highest total phenolics (78.65 ± 3.58 mg GAE/g DW) and flavonoids (22.15 ± 4.66 mg CE/g DW). In contrast, this fraction displayed the highest DPPH• scavenging ability with IC50 values of 0.06 ± 0.003 mg/mL. The RP-HPLC-PDA analysis of phenolic compounds from leaves of C. cheirifolium lets to identify: rosmarinic acid, ferulic acid, caffeic acid, p-coumaric acid, syringic acid, sinapic acid and rutin. The obtained results indicate that this plant represent a valuable source of natural antioxidants. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|