Effects of Protein Isolates from Radish and Spinach Leaves on Serum Lipids Levels in Rats
| Autor: | Tsutomu Satoh, Masahiko Goto, Kiharu Igarashi |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
genetic structures Medicine (miscellaneous) Blood lipids Plant Proteins Dietary Intestinal absorption Feces chemistry.chemical_compound Casein Animals Food science Amino Acids Rats Wistar Nutrition and Dietetics Methionine biology Cholesterol Protein isolate Serum cholesterol level equipment and supplies biology.organism_classification Lipids eye diseases Rats Liver chemistry Biochemistry Spinach Steroids sense organs |
| Zdroj: | Journal of Nutritional Science and Vitaminology. 39:627-633 |
| ISSN: | 1881-7742 0301-4800 |
| DOI: | 10.3177/jnsv.39.627 |
| Popis: | Radish and spinach leaf protein isolates (RLP and SLP, respectively) were prepared from chilled aqueous 0.2% sodium hydroxide extract of their leaves. The RLP and SLP, and those supplemented with methionine (RLP + Met and SLP + Met, respectively) to become equal to casein in methionine content, were compared with casein for their effects on serum cholesterol level in rats fed with a cholesterol-enriched diet for 14 days. Each protein isolate was incorporated into the cholesterol-enriched diet to provide a 15% protein level. RLP was extremely inferior to SLP and casein for body weight gain of rats, but that of rats fed with RLP + Met diet was almost equal to that of casein and SLP groups. The serum cholesterol level in rats fed with SLP and SLP + Met diets was significantly lower as compared with that of the casein-fed rats. Both the amounts of excreted cholesterol and bile acids were significantly higher in rats fed with the SLP and SLP + Met diets than that of the casein-fed rats. These results suggest that the hypocholesterolemic action of SLP may in part have been due to the inhibition of intestinal absorption of both cholesterol and bile acids. RLP + Met diet tended to decrease the serum cholesterol level as compared to casein diet, but the difference was not significant. |
| Databáze: | OpenAIRE |
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