The effectiveness of mammography surveillance after treatment of primary breast cancer: A single centre retrospective cohort study
| Autor: | Wafa Taher, John R. Benson, Sam Leinster |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
03 medical and health sciences 0302 clinical medicine Recurrence Internal medicine medicine Chi-square test Mammography Breast Cohort Study Cancer Surveillance medicine.diagnostic_test business.industry Mammogram Retrospective cohort study General Medicine medicine.disease Detection Single centre 030220 oncology & carcinogenesis Cohort 030211 gastroenterology & hepatology Surgery Observational study business Primary breast cancer |
| Zdroj: | Annals of Medicine and Surgery |
| ISSN: | 2049-0801 |
| Popis: | Introduction There is a little evidence that routine follow-up of patients treated for early breast cancer (BC) to detect ibsilateral breast tumour recurrence (IBTR), or contralateral breast cancer (CBC), is either effective or offers any mortality benefits. We report our experience of following patients with early BC for recurrences and new primaries in order to determine the role of mammogram surveillance. Methods Single centre, retrospective primary observational study was designed. Patients who had BC during year 2001–2006 were included and followed for a minimum of ten years. Patients were divided based on the modalities of detecting BC in to screen detected group and clinically detected one i.e. symptomatic BC. These two groups were compared. Results Total number of patients considered for analysis was 2530 (screen detected BC - 703 patients and symptomatic BC - 1827 patients). The rate of recurrence including regional and distant metastasis in screen detected BC group was 8% (57/703) and 2% (43/1827) in symptomatic one. However, the prevalence of IBTR/CBC in the whole cohort was 2% (62/2530). Mammography surveillance identified 60% (37/62) of patients who had IBTRs/CBCs. Mammography surveillance detected 85% (29/34) of all IBTRs/CBCs in the screen detected BC group. In contrast, it picked up only 29% (8/28) in the other group (Chi squared 20.5 p Highlights • Currently there is no randomised controlled trials demonstrating benifits of surveillance mammography. • Mammogram follow-up is efficient for the screen-detected group but not for the clinically detected once. |
| Databáze: | OpenAIRE |
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