Optic Neuropathy Complicating Multifocal Choroiditis and Panuveitis
| Autor: | Susan E Wittenberg, Jennifer E. Thorne, Sanjay Kedhar, James P. Dunn, Douglas A. Jabs |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Choroiditis Visual acuity genetic structures Eye disease Visual Acuity Article Optic neuropathy Recurrence Prednisone Optic Nerve Diseases Panuveitis medicine Humans Cranial nerve disease Retrospective Studies business.industry Middle Aged medicine.disease eye diseases Surgery Ophthalmology Female sense organs medicine.symptom business Complication Immunosuppressive Agents Follow-Up Studies medicine.drug |
| Zdroj: | American Journal of Ophthalmology. 143:721-723 |
| ISSN: | 0002-9394 |
| Popis: | Purpose To describe the clinical characteristics of patients with optic neuropathy complicating multifocal choroiditis and panuveitis (MFCPU). Design Retrospective case series. Methods Eight patients (11 eyes) with MFCPU and optic neuropathy from a single center were reviewed and clinical outcomes described. Results The median age of patients was 45 years; six patients were women and seven were Caucasian. In the six patients with available follow-up, the optic neuropathy was corticosteroid-responsive, but required corticosteroid treatment to prevent recurrences of optic nerve inflammation and subsequent vision loss. Five patients required immunosuppressive drug therapy during their treatment course. No patients had recurrence of optic neuropathy while receiving immunosuppressive drug therapy. Visual acuity improved or stabilized with treatment in nine of 11 affected eyes. Conclusions Optic neuropathy is an uncommon complication of MFCPU that may result in substantial visual morbidity. Immunosuppressive drug therapy may prevent recurrences of optic neuropathy and subsequent vision loss. |
| Databáze: | OpenAIRE |
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