Chronic vascular catheterization in the rat: comparison of three techniques
| Autor: | Byron C. Yoburn, Rudy Morales, Charles E. Inturrisi |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
medicine.medical_specialty Experimental and Cognitive Psychology Femoral artery Body weight Catheterization Behavioral Neuroscience Catheters Indwelling Catheterization procedure Weight loss Jugular vein medicine.artery medicine Animals cardiovascular diseases Blood Specimen Collection business.industry Rats Inbred Strains Cannula Surgery Rats Femoral Artery surgical procedures operative medicine.anatomical_structure Carotid Arteries Anesthesia cardiovascular system medicine.symptom Jugular Veins business therapeutics Blood vessel Blood sampling |
| Zdroj: | Physiologybehavior. 33(1) |
| ISSN: | 0031-9384 |
| Popis: | Rats were implanted with an indwelling vascular cannula in the jugular vein, femoral artery or carotid artery, and evaluated for postsurgical weight changes and cannula patency. Complete details for surgical methods and materials are presented for each procedure. Over a 14 day period, the carotid artery procedure produced the most profound weight loss, while the jugular vein implantation was followed by minimal changes in body weight. Weight loss was intermediate for the femoral artery group. Body weight had returned to, or was above presurgical weight at 2, 4 and 6 days postsurgery for the jugular, femoral and carotid catheterizations, respectively. By 14 days following implantation 83%, 67% and 50% of the femoral, carotid and jugular cannulas, respectively, were patent. We conclude that for long-term sampling of blood in the rat, the femoral artery catheterization procedure is preferable in terms of patency and postsurgical weight loss. |
| Databáze: | OpenAIRE |
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