Pain incidence in cervical dystonia is determined by the disease phenotype
| Autor: | Sylwia Popek-Marciniec, Michał Marciniec, Konrad Rejdak, Anna Szczepańska-Szerej |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Physical examination 03 medical and health sciences 0302 clinical medicine Pain assessment Physiology (medical) Internal medicine medicine Humans Cervical dystonia Clinical phenotype Torticollis Neck Pain medicine.diagnostic_test business.industry Incidence Incidence (epidemiology) Medical record Repetitive movements General Medicine Middle Aged medicine.disease Pathophysiology Phenotype Neurology 030220 oncology & carcinogenesis Female Surgery Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Clinical Neuroscience. 79:133-136 |
| ISSN: | 0967-5868 |
| DOI: | 10.1016/j.jocn.2020.07.069 |
| Popis: | Cervical dystonia (CD) is a movement disorder caused by prolonged contractions of the head and neck muscles resulting in abnormal postures and repetitive movements. Depending on the direction of the head and neck deviation, CD phenotypes are divided into torti-, latero-, antero-, and retro- impairments assessed in commonly used TWSTRS classification, or -caput and -collis according to the novel Col-Cap concept. Cervical pain, which pathophysiology has not been fully elucidated, affects more than 60% of CD patients. To date, none of the studies have investigated the risk of pain associated with the particular disease phenotype.In this observational study data collection was based on the survey completion by the participants, analysis of the medical records, and physical examination with the use of proper scales (TWSTRS, Col-Cap, Tsui). Extended pain profile questionnaire included detailed questions about pain localization, character, and intensity.We examined 60 patients suffered from CD; 66,7% of them reported cervical pain. Latero- as the only TWSTRS phenotype was associated with increased risk of pain occurrence (OR = 3,95; p 0,05). Interestingly, each of two Col-Cap phenotypes correlated with cervical pain: -caput positively (OR = 3,78; p 0,05) and -collis negatively (OR = 0,29; p 0,05).The risk of dystonic pain was highly differentiated within the particular CD phenotypes. The enhanced risk of cervical pain was observed in latero- (TWSTRS) and -caput (Col-Cap) phenotypes; conversely, -collis type (Col-Cap) was characterized by the lowest risk of cervical pain. |
| Databáze: | OpenAIRE |
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