Delayed toxic effects of sulfur mustard on respiratory tract of Iranian veterans
| Autor: | Hadi Kahrom, Davood Attaran, Gholam Ali Zare, Reza Afshari, Seyed Reza Mousavi, Mahdi Balali-Mood, Maedeh Kamrani, Ramin Zojaji |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Warfare Time Factors Health Toxicology and Mutagenesis Respiratory Tract Diseases Poison control Iran Toxicology Gastroenterology Severity of Illness Index Pulmonary function testing Risk Factors Internal medicine Diabetes mellitus Mustard Gas medicine Humans Disabled Persons Chemical Warfare Agents Respiratory system Aged Veterans Bronchiectasis business.industry Respiratory disease General Medicine Middle Aged medicine.disease Surgery Respiratory Function Tests Oxygen medicine.anatomical_structure Blood pressure business Respiratory tract |
| Zdroj: | Humanexperimental toxicology. 30(9) |
| ISSN: | 1477-0903 |
| Popis: | To investigate late toxic effects of sulfur mustard (SM) on the upper and lower respiratory tracts of Iranian veterans, 43 male veterans with more than 25% disability due to SM poisoning in 20−25 years after exposure, were studied. Direct laryngoscopy, pulmonary function tests, arterial blood gasses and pH, computed tomography of sinuses and lungs were investigated. The patients were aged 50.6 (8.9 SD) years with body mass index (BMI) of 26.6 (4.0) and disability of 53.2 (17.0%). The common findings of the upper respiratory tract were dysphonia (79.1%), post-nasal discharge (PND; 41.9%), lower larynx position (30.2%), limitation of vocal cords (25.6%) and mucosal inflammation of larynx (14.8%). The common lower respiratory diseases were diagnosed as chronic obstructive respiratory disease (84%), bronchiectasis (44.1%) and lung fibrosis (7.7%). Severity of disability was negatively correlated with BMI ( p = 0.032), spirometric parameters ( p < 0.001) and oxygen saturation ( p < 0.001), but positively correlated with low-density lipoproteins (LDL |
| Databáze: | OpenAIRE |
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