Correlation between adenoma detection rate in colonoscopy- and fecal immunochemical testing-based colorectal cancer screening programs
| Autor: | María Chaparro, Maria Sala, Manuel Hernandez-Guerra, Cristina Rodríguez de Miguel, Luis Bujanda, Agustín Seoane Urgorri, Vicent Hernandez, Xavier Bessa Caserras, Guillermo Cacho Acosta, Maria Pellise, Jaume Grau, Francisca Gonzalez Rubio, Francesc Balaguer, JOAQUIN CUBIELLA, Cecilio Santander Vaquero, Inmaculada Salces, Antonio Z Gimeno-Garcia, Antoni Castells, Marta Carrillo-Palau, Renata Linertová, Enrique Quintero |
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| Rok vydání: | 2016 |
| Předmět: |
Oncology
medicine.medical_specialty medicine.diagnostic_test Adenoma business.industry Confounding Gastroenterology Colonoscopy Colorectal adenoma Original Articles medicine.disease Correlation 03 medical and health sciences 0302 clinical medicine Colorectal cancer screening 030220 oncology & carcinogenesis Internal medicine medicine 030211 gastroenterology & hepatology Detection rate business Feces |
| Zdroj: | United European gastroenterology journal. 5(2) |
| ISSN: | 2050-6406 |
| Popis: | The adenoma detection rate (ADR) is the main quality indicator of colonoscopy. The ADR recommended in fecal immunochemical testing (FIT)-based colorectal cancer screening programs is unknown.Using the COLONPREV (NCT00906997) study dataset, we performed a post-hoc analysis to determine if there was a correlation between the ADR in primary and work-up colonoscopy, and the equivalent figure to the minimal 20% ADR recommended. Colonoscopy was performed in 5722 individuals: 5059 as primary strategy and 663 after a positive FIT result (OC-Sensor™; cut-off level 15 µg/g of feces). We developed a predictive model based on a multivariable lineal regression analysis including confounding variables.The median ADR was 31% (range, 14%-51%) in the colonoscopy group and 55% (range, 21%-83%) in the FIT group. There was a positive correlation in the ADR between primary and work-up colonoscopy (Pearson's coefficient 0.716;ADR in primary and work-up colonoscopy of a FIT-positive result are positively and significantly correlated. |
| Databáze: | OpenAIRE |
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