The red pigment prodigiosin is not an essential virulence factor in entomopathogenic Serratia marcescens
Autor: | Lin Zhang, Wan Yongji, Jing‐Hua Li, Jie Chen, Wei Zhou, Tingting Xiang, Xiaoyuan Liu |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Virulence Factors 030106 microbiology Mutant Virulence Virulence factor Serratia Infections Microbiology Prodigiosin 03 medical and health sciences chemistry.chemical_compound Pigment Animals Serratia marcescens Ecology Evolution Behavior and Systematics Larva biology Strain (chemistry) Bombyx biology.organism_classification 030104 developmental biology chemistry visual_art visual_art.visual_art_medium sense organs |
Zdroj: | Journal of Invertebrate Pathology. 136:92-94 |
ISSN: | 0022-2011 |
DOI: | 10.1016/j.jip.2016.03.011 |
Popis: | Although pigments produced by pathogenic microbes are generally hypothesized as essential virulence factors, the role of red pigment prodigiosin in the pathogenesis of entomopathogenic Serratia marcescens is not clear. In this study, we analyzed the pathogenicity of different pigmented S. marcescens strains and their non-pigmented mutants in silkworms. Each pigmented strain and the corresponding non-pigmented mutants showed very similar LD50 value (statistically no difference), but caused very different symptom (color of the dead larva). Our results clearly indicated that the red pigment prodigiosin is not an essential virulence factor in entomopathogenic S. marcescens. |
Databáze: | OpenAIRE |
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