Characteristics and outcomes of reversed patients admitted to an emergency department for VKA-related intramuscular hematoma
| Autor: | Frédéric Dutheil, N. Breuil, L. Poujol, J. Saint-Denis, Jeannot Schmidt, Nicolas Dublanchet, Farès Moustafa, N. Vincent, S. Heuser, Aurélien Lebreton |
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| Přispěvatelé: | Pôle Urgences [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Université Clermont Auvergne (UCA), CHU Clermont-Ferrand, Laboratoire de Psychologie Sociale et Cognitive (LAPSCO), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Service Santé Travail Environnement [CHU Clermont-Ferrand], WittyFit |
| Rok vydání: | 2017 |
| Předmět: |
Male
Vitamin K Emergency unit medicine.drug_class Intramuscular hematoma 030204 cardiovascular system & hematology Major bleeding 03 medical and health sciences 0302 clinical medicine Hematoma Muscular Diseases medicine Humans 030212 general & internal medicine Aged Retrospective Studies Inpatients business.industry VKA Anticoagulants [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology General Medicine Emergency department Vitamin K antagonist medicine.disease Prognosis Thrombosis Blood Coagulation Factors 3. Good health Anesthesia ISTH criteria Emergency Medicine Oral anticoagulant Female business Emergency Service Hospital PROTHROMBIN COMPLEX [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology Follow-Up Studies |
| Zdroj: | The American Journal of Emergency Medicine The American Journal of Emergency Medicine, 2018, 36 (7), pp.1257-1261. ⟨10.1016/j.ajem.2018.03.067⟩ American Journal of Emergency Medicine American Journal of Emergency Medicine, 2018, 36 (7), pp.1257-1261. ⟨10.1016/j.ajem.2018.03.067⟩ |
| ISSN: | 1532-8171 0735-6757 |
| Popis: | International audience; BackgroundAccording to the International Society on Thrombosis and Haemostasis (ISTH), intramuscular hematoma without other severity criteria is not considered a major bleeding. Objectives: In a large cohort of reversed vitamin K antagonist (VKA) patients admitted to the emergency unit for muscular hematoma, we assess frequency, severity, and anticoagulation management based on whether ISTH criteria were met or not.Materials and methodsWe performed a retrospective single-center study involving patients admitted to an emergency unit for VKA-induced intramuscular hematoma whose bleeding was reversed with prothrombin complex concentrates.ResultsDuring the study period, 631 VKA-induced bleeding events occurred in our emergency unit, of which 73 (11.6%) were intramuscular hematomas and half met ISTH criteria. The mean age was 75.5years (95% CI=72.6–78.3). Admission blood tests showed that patients with ISTH criteria had higher international normalized ratio (7.0±4.6 vs. 4.1±3.0, p=0.002) and lower hemoglobin (8.1±1.8 vs. 11.9±2.2, p |
| Databáze: | OpenAIRE |
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