p53 and anti-p53 antibodies as possible markers of a switch towards a neoplastic phenotype in patients infected by Helicobacter pylori
| Autor: | F. Rossano, David L. Hasty, L. Ortega de luna, E. Losi, M.T. Fera, M.R Catania, Patrizia Gazzerro, M. Carbone, Anna Maria Molinari |
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| Přispěvatelé: | Losi, E, Molinari, Am, Gazzerro, P, ORTEGA DE LUNA, L, Fera, Mt, Carbone, M, Catania, MARIA ROSARIA, Hasty, Dl, Rossano, Fabio, Molinari, Anna Maria, Catania, Mr, Rossano, F. |
| Předmět: |
p53
General Biochemistry Genetics and Molecular Biology Antibodies Helicobacter Infections History and Philosophy of Science Medicine Humans In patient P53 antibodies Carcinogen biology Helicobacter pylori business.industry General Neuroscience biology.organism_classification anti-p53 Phenotype Cell Transformation Neoplastic Mechanism of action antibodie P53 protein Immunology biology.protein medicine.symptom Antibody Tumor Suppressor Protein p53 business |
| Zdroj: | Europe PubMed Central |
| Popis: | Helicobacter pylori is a definite carcinogen whose mechanism of action is still unknown. The aim of this work was (1) to determine the presence of p53 protein and related antibodies in patients affected by various gastric pathologies and chronically infected with H. pylori, and (2) to try to discover a test to be used as a marker of a possible switch towards a neoplastic phenotype. |
| Databáze: | OpenAIRE |
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