Epidemiology of congenital Chagas disease 6 years after implementation of a public health surveillance system, Catalonia, 2010 to 2015
| Autor: | Basile, Luca, Ciruela, Pilar, Requena-Méndez, Ana, Vidal, Mª José, Dopico, Eva, Martín Nalda, Andrea, Sulleiro, Elena, Gascón i Brustenga, Joaquim, Jané, Mireia, Working Group Of Congenital Chagas Disease In Catalonia, Gállego Culleré, M. (Montserrat) |
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| Přispěvatelé: | Institut Català de la Salut, [Basile L, Vidal MJ] Agència de Salut Pública de Catalunya, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. [Ciruela P] CIBER en Epidemiologia i Salut Pública (CIBERESP), Madrid, Spain. Instituto de Salud Carlos III, Madrid, Spain. Agència de Salut Pública de Catalunya, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. [Requena-Méndez A] ISGlobal, Hospital Clínic de Barcelona, Barcelona, Spain. [Dopico E] Laboratori Clínic de l'Hospitalet, Hospitalet de Llobregat, Barcelona, Spain. [Martín-Nalda A] Unitat de Patologia Infecciosa i Immunodeficiències de Pediatria, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Vall d’Hebron Institut de Recerca, Barcelona, Spain. Universitat Autònoma de Barcelona (UAB), Barcelona, Spain. [Sulleiro E] Servei de Microbiologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona (UAB), Barcelona, Spain., Vall d'Hebron Barcelona Hospital Campus |
| Rok vydání: | 2019 |
| Předmět: |
Chagas disease
Otros calificadores::Otros calificadores::/prevención & control [Otros calificadores] Pediatrics Epidemiology Prevalence Other subheadings::Other subheadings::/congenital [Other subheadings] Investigative Techniques::Epidemiologic Methods::Data Collection::Surveys and Questionnaires::Health Surveys::Population Surveillance::Public Health Surveillance [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT] Serology enfermedades parasitarias::infecciones por protozoos::infecciones por Euglenozoa::tripanosomiasis::enfermedad de Chagas [ENFERMEDADES] Screening programme Congenital Malaltia de Chagas Public health surveillance Pregnancy Mass Screening Medicine Public Health Surveillance Pregnancy Complications Infectious técnicas de investigación::métodos epidemiológicos::recopilación de datos::encuestas y cuestionarios::encuestas de salud::vigilancia de la población::vigilancia en salud pública [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS] Surveillance system Public health Surveillance Otros calificadores::Otros calificadores::/congénito [Otros calificadores] public health Chagas Malaltia de - Epidemiologia - Catalunya Child Preschool Prenatal Exposure Delayed Effects Screening Vertical transmission Female Parasitic Diseases::Protozoan Infections::Euglenozoa Infections::Trypanosomiasis::Chagas Disease [DISEASES] Adult medicine.medical_specialty Catalonia Trypanosoma cruzi Salut pública - Avaluació surveillance system Other subheadings::Other subheadings::/prevention & control [Other subheadings] Cataluña Virology parasitic diseases Humans Serologic Tests business.industry screening Infant Newborn congenital Public Health Environmental and Occupational Health Infant Catalunya medicine.disease Chagas' disease Spain vertical transmission business Follow-Up Studies |
| Zdroj: | Scientia Dipòsit Digital de la UB Universidad de Barcelona Recercat. Dipósit de la Recerca de Catalunya instname Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Eurosurveillance |
| ISSN: | 1560-7917 |
| DOI: | 10.2807/1560-7917.es.2019.24.26.19-00011 |
| Popis: | Background Chagas disease is endemic in Latin America and affects 8 million people worldwide. In 2010, Catalonia introduced systematic public health surveillance to detect and treat congenital Chagas disease. Aim The objective was to evaluate the health outcomes of the congenital Chagas disease screening programme during the first 6 years (2010–2015) after its introduction in Catalonia. Methods In a surveillance system, we screened pregnant women and newborns and other children of positive mothers, and treated Chagas-positive newborns and children. Diagnosis was confirmed for pregnant women and children with two positive serological tests and for newborns with microhaematocrit and/or PCR at birth or serology at age 9 months. Results From 2010 to 2015, the estimated screening coverage rate increased from 68.4% to 88.6%. In this period, 33,469 pregnant women were tested for Trypanosoma cruzi and 937 positive cases were diagnosed. The overall prevalence was 2.8 cases per 100 pregnancies per year (15.8 in Bolivian women). We followed 82.8% of newborns until serological testing at age 9–12 months and 28 were diagnosed with Chagas disease (congenital transmission rate: 4.17%). Of 518 siblings, 178 (34.3%) were tested and 14 (7.8%) were positive for T. cruzi. Having other children with Chagas disease and the heart clinical form of Chagas disease were maternal risk factors associated with congenital T. cruzi infection (p Conclusion The increased screening coverage rate indicates consolidation of the programme in Catalonia. The rate of Chagas disease congenital transmission in Catalonia is in accordance with the range in non-endemic countries. |
| Databáze: | OpenAIRE |
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