Association between perceived social support and Th1 dominance
| Autor: | Fumio Kobayashi, Noriyuki Kawamura, Toshio Ishikawa, Akinori Nakata, Osamu Fujita, Takashi Haratani, Akiko Miki, Yousuke Fujioka, Hirofumi Iimori, Shotaro Sakami, Takao Miyazaki, Takashi Sakurai |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Motor Activity Developmental psychology Natural killer cell Interferon-gamma Leukocyte Count Social support Immune system Surveys and Questionnaires medicine Humans Workplace Natural Killer Cell Count Social perception General Neuroscience Smoking Stressor Social Support T-Lymphocytes Helper-Inducer Flow Cytometry Killer Cells Natural Neuropsychology and Physiological Psychology Dominance (ethology) medicine.anatomical_structure CD4 Antigens Perception Interleukin-4 Psychology Stress Psychological Psychoneuroimmunology |
| Zdroj: | Biological Psychology. 70:30-37 |
| ISSN: | 0301-0511 |
| DOI: | 10.1016/j.biopsycho.2004.09.004 |
| Popis: | Social support is supposed to have a positive health effect via alteration of immunity. In this study, associations between perceived social support and immune systems were examined. Immunological assessments, e.g. T cell count, Natural Killer cell count, Interferon-gamma, Interleukin-4, and psychological assessments, e.g. Generic Job Stress Questionnaire were conducted on male employees. Two-way (social support x job stressor) analyses of covariance controlling for age, smoking, alcohol consumption, and exercise revealed that there were main effects of perceived social support on NK cell counts, IL-4, and Th1/Th2 balance. On the other hand, interaction effects were observed on T cell counts and INF-gamma production in vitro. Social support affects immune function in a way that is consistent with both the direct and buffering hypotheses depending on the sources of support and the immune parameter. |
| Databáze: | OpenAIRE |
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