Smoking and mortality following acute myocardial infarction: results from the National Registry of Myocardial Infarction 2 (NRMI 2)

Autor: Amy Chen Rundle, Hal V. Barron, Steven G. Gourlay
Rok vydání: 2002
Předmět:
Zdroj: Nicotine & Tobacco Research. 4:101-107
ISSN: 1469-994X
1462-2203
Popis: Background : Current smokers have lower mortality following acute myocardial infarction (AMI) than non-smokers. This is often referred to as the ‘smokers' paradox’. Our study explored possible explanations of this phenomenon. Methods: From the 510,044 cases of AMI in the NRMI 2 from 1 June 1994, through 30 April 1997, 297,458 cases without hospital transfer were analyzed. Characteristics and treatments of tobacco smokers and non-smokers were compared before and after age-standardization. Multivariate logistic models investigated possible associations with in-hospital mortality using clinically relevant variables and interaction terms. Results: Twenty-four per cent of AMI cases were current smokers. Smokers were 14 years younger than non-smokers (mean age 58 vs. 72 years, p
Databáze: OpenAIRE