Cariogenic microflora in patients with Hodgkin's disease before and after mantle field radiotherapy
| Autor: | Terence J. Fleming, Harris J. Keene, Bela B. Toth |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Adolescent medicine.medical_treatment Dentistry Disease Dental Caries Xerostomia Pathology and Forensic Medicine Streptococcus mutans chemistry.chemical_compound Carious teeth medicine Humans General Dentistry Saline Aged Mouth Radiotherapy biology DMF Index business.industry Mantle Field Middle Aged medicine.disease biology.organism_classification Hodgkin Disease Lymphoma Radiation therapy Lactobacillus stomatognathic diseases Cross-Sectional Studies chemistry Tin Fluorides Female Lymph Nodes business Gels Fluoride |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology. 78:577-582 |
| ISSN: | 0030-4220 |
| DOI: | 10.1016/0030-4220(94)90167-8 |
| Popis: | Because mantle field radiotherapy is associated with partial xerostomia in patients with Hodgkin's disease, the purpose of this study was to evaluate their cariogenic microflora before and after completion of radiotherapy. We obtained samples of oral saline solution rinse from 40 patients with Hodgkin's disease before radiotherapy and from 31 patients with Hodgkin's disease who had survived 1 to 24 years after radiotherapy. We also evaluated caries experience and history of fluoride gel use for caries prevention in these patients. Mutans streptococci and lactobacilli levels were significantly higher in the postradiotherapy patients with carious teeth, particularly in those with limited home use of fluoride gels. In the postradiotherapy group, caries parameters were significantly higher (p < 0.05) than in the preradiotherapy group. Within the postradiotherapy group, both caries and microbial parameters tended to be higher in patients who were less compliant about using the recommended 0.4% stannous fluoride "brush-in" technique than in those who used the gel regularly at home. This study indicates that for patients with Hodgkin's disease who receive mantle field irradiation during the management of their disease, a sustained brush-in program with stannous fluoride gel can be of benefit for caries prevention and for limitation of oral levels of cariogenic mutans streptococci. |
| Databáze: | OpenAIRE |
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