The return of copy-choice in DNA recombination
| Autor: | Roderick S. Tang |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Genetics
DNA Replication DNA Bacterial Recombination Genetic DNA Plant Models Genetic DNA replication Context (language use) Biology General Biochemistry Genetics and Molecular Biology law.invention chemistry.chemical_compound chemistry law DNA Viral Homologous chromosome Recombinant DNA DNA Transposable Elements Direct repeat Crossing Over Genetic Dna viral DNA Recombination Repetitive Sequences Nucleic Acid Sequence Deletion |
| Zdroj: | BioEssays : news and reviews in molecular, cellular and developmental biology. 16(11) |
| ISSN: | 0265-9247 |
| Popis: | In a recent publication, d'Alencon et al.(1) presented evidence that a form of non-homologous DNA recombination involving direct repeats is dependent upon the replication of the DNA. In addition, density-labeling experiments showed that after recombination was stimulated, progenies were present only in molecules that had undergone complete replication. These observations are consistent with a replicative and not a breakage-and-rejoining model for the DNA recombination events. These two models had of course been contrasted many years ago in mechanistic studies of homologous DNA recombination. It is therefore interesting to place the latest findings of d'Alencon et al. in this historical context. |
| Databáze: | OpenAIRE |
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