Eigenlenses: a new model for full crystalline lens shape representation and its applications
| Autor: | Alberto de Castro, Eduardo Martinez-Enriquez, Susana Marcos |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
medicine.diagnostic_test business.industry Image quality Extrapolation Presbyopia medicine.disease 01 natural sciences Atomic and Molecular Physics and Optics Article law.invention 010309 optics Lens (optics) 03 medical and health sciences 0302 clinical medicine Optics Optical coherence tomography law 0103 physical sciences 030221 ophthalmology & optometry medicine Representation (mathematics) business Biotechnology |
| Zdroj: | Biomed Opt Express |
| Popis: | The crystalline lens is an important optical element in the eye, responsible for focusing, and which experiences significant changes throughout life. The shape of the lens is usually studied only in the optical area (central 4 to 6 mm). However, for a great number of applications, a description of the full shape of the crystalline lens is required. We propose a new method for the representation of the full shape of the crystalline lens, constructed from 3-dimensional optical coherence tomography images of 133 isolated crystalline lenses (0-71 y/o), which we have called eigenlenses. The method is shown to be compact and accurate to describe not only the full shape of the crystalline lens, but also the optical zone in comparison with other methods. We also demonstrate its application to the extrapolation of the full shape of the crystalline lens from in-vivo optical images of the anterior segment of the eye, where only the central part of the lens visible through the pupil is available, and in the generation (synthesis) of realistic full lenses of a given age. The method has critical applications, among others, in improving and evaluating myopia and presbyopia treatments. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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