Benefits of superficial hyperthermia treatment planning: Five case studies

Autor:	J. van der Zee, M. de Bruijne, G. C. Van Rhoon, Nicolas Chavannes, D. H. M. Wielheesen
Přispěvatelé:	Radiation Oncology
Rok vydání:	2007
Předmět:	Male Cancer Research medicine.medical_specialty Skin Neoplasms Physiology Superficial hyperthermia Breast Neoplasms Models Biological Patient Care Planning Physiology (medical) Intensive care Humans Medicine Medical physics Radiation treatment planning Melanoma Clinical treatment Aged Aged 80 and over business.industry Treatment options Hyperthermia Induced Limiting Middle Aged Prognosis Clinical routine Surgery Carcinoma Merkel Cell Treatment Outcome Female Model implementation business Neurilemmoma Bone Wires
Zdroj:	International Journal of Hyperthermia, 23(5), 417-429. Informa Healthcare
ISSN:	1464-5157 0265-6736
Popis:	Purpose: To demonstrate the benefits of treatment planning in superficial hyperthermia. Materials and methods: Five patient cases are presented, in which treatment planning was applied to troubleshoot treatment-limiting hotspots, to select the optimum applicator type and orientation, to assess the risk associated with metallic implants, to assess the feasibility of heating a deeper seated tumour, and to analyse the effective SAR coverage resulting from arrays of multiple incoherent applicators. FDTD simulation tools were used to investigate treatment options, either based on segmented or simplified anatomies. Results: The background, approach and model implementation are presented per case. SAR cross-sections, profiles and isosurfaces are visualized to predict the effective SAR coverage of the target and the location of the maximum power absorption. In addition, the followed treatment strategy and the implications for the clinical treatment are given: for example, higher temperatures, relief of treatment limiting hot-spots or increased power input. Conclusions: Treatment planning in superficial hyperthermia can be applied to improve clinical routine. Its application supports the selection of the optimum technique in non-standard cases, leading to direct benefits for the patient. In addition, treatment planning has shown to be an excellent tool for education and training for hyperthermia technicians and physicians.
Databáze:	OpenAIRE
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