Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles
| Autor: | Benjamín Valdez-Salas, Jorge Salvador-Carlos, Roberto Ibarra-Wiley, Mario Curiel-Alvarez, Ernesto Beltrán-Partida, Ernesto Valdez-Salas, Nelson Cheng |
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| Rok vydání: | 2021 |
| Předmět: |
Disinfectant
Pharmaceutical Science Metal Nanoparticles 02 engineering and technology Chick Embryo 01 natural sciences Silver nanoparticle Anti-Infective Agents X-Ray Diffraction International Journal of Nanomedicine surgical mask Drug Discovery Spectroscopy Fourier Transform Infrared Medicine Original Research Waste management Textiles Masks General Medicine 021001 nanoscience & nanotechnology Antimicrobial 0210 nano-technology Silver Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Biophysics Bioengineering Microbial Sensitivity Tests 010402 general chemistry Antiviral Agents nanobiotechnology Biomaterials Equipment Reuse Animals Humans Health professionals Influenza A Virus H5N1 Subtype business.industry SARS-CoV-2 Organic Chemistry COVID-19 Dynamic Light Scattering 0104 chemical sciences Disinfection Surgical mask antimicrobial nanoparticles business Disinfectants |
| Zdroj: | International Journal of Nanomedicine |
| ISSN: | 1178-2013 5268-6566 |
| Popis: | Benjamin Valdez-Salas,1,2 Ernesto Beltran-Partida,1,2 Nelson Cheng,3 Jorge Salvador-Carlos,2 Ernesto Alonso Valdez-Salas,1 Mario Curiel-Alvarez,2 Roberto Ibarra-Wiley2 1Laboratorio de Biología Molecular y Cáncer, Instituto de Ingeniería, Universidad Autónoma de Baja California, Mexicali, Baja California, Mexico; 2Laboratorio de Corrosión y Materiales Avanzados, Instituto de Ingeniería, Universidad Autónoma de Baja California, Mexicali, Baja California, Mexico; 3Magna International Pte Ltd, SingaporeCorrespondence: Benjamin Valdez-Salas Tel/Fax +526865664154 Ext. 150Email benval@uabc.edu.mxBackground: The COVID-19 pandemic is requesting highly effective protective personnel equipment, mainly for healthcare professionals. However, the current demand has exceeded the supply chain and, consequently, shortage of essential medical materials, such as surgical masks. Due to these alarming limitations, it is crucial to develop effective means of disinfection, reusing, and thereby applying antimicrobial shielding protection to the clinical supplies.Purpose: Therefore, in this work, we developed a novel, economical, and straightforward approach to promote antimicrobial activity to surgical masks by impregnating silver nanoparticles (AgNPs).Methods: Our strategy consisted of fabricating a new alcohol disinfectant formulation combining special surfactants and AgNPs, which is demonstrated to be extensively effective against a broad number of microbial surrogates of SARS-CoV-2.Results: The present nano-formula reported a superior microbial reduction of 99.999% against a wide number of microorganisms. Furthermore, the enveloped H5N1 virus was wholly inactivated after 15 min of disinfection. Far more attractive, the current method for reusing surgical masks did not show outcomes of detrimental amendments, suggesting that the protocol does not alter the filtration effectiveness.Conclusion: The nano-disinfectant provides a valuable strategy for effective decontamination, reuse, and even antimicrobial promotion to surgical masks for frontline clinical personnel.Keywords: surgical mask, antimicrobial, SARS-CoV-2, nanobiotechnology, COVID-19, nanoparticles |
| Databáze: | OpenAIRE |
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