A retrospective study of an invasive versus conservative strategy in patients aged ≥80 years with acute ST-segment elevation myocardial infarction

Autor: Si-Yong Teng, Yong-Gang Sui, Shubin Qiao, Yi-Da Tang, Yongjian Wu, Kefei Dou, Jie Qian, Yuan Wu
Rok vydání: 2019
Předmět:
Medicine (General)
medicine.medical_specialty
Invasive strategy
Clinical Research Reports
Acute ST segment elevation myocardial infarction
conservative strategy
030204 cardiovascular system & hematology
Conservative Treatment
Biochemistry
03 medical and health sciences
R5-920
0302 clinical medicine
Older patients
Internal medicine
Humans
Medicine
In patient
invasive strategy
Hospital Mortality
cardiovascular diseases
030212 general & internal medicine
Myocardial infarction
Retrospective Studies
Aged
80 and over

business.industry
Biochemistry (medical)
Retrospective cohort study
Cell Biology
General Medicine
Prognosis
medicine.disease
older patients
Conservative strategy
ST-segment elevation myocardial infarction
Logistic Models
Multivariate Analysis
Cardiology
ST Elevation Myocardial Infarction
business
Cohort study
Zdroj: Journal of International Medical Research, Vol 47 (2019)
The Journal of International Medical Research
ISSN: 1473-2300
0300-0605
DOI: 10.1177/0300060519860969
Popis: Objective To investigate what is the most appropriate strategy for patients with ST-segment elevation myocardial infarction (STEMI) aged ≥80 years in China. Methods This cohort study retrospectively enrolled patients with STEMI aged ≥80 years old and grouped them according to the treatment strategy that was used: a conservative treatment strategy or an invasive treatment strategy. Factors associated with whether to perform an invasive intervention, in-hospital death and a good prognosis were investigated using logistic regression analyses. Results A total of 232 patients were enrolled: conservative treatment group ( n = 93) and invasive treatment group ( n = 139). Patients in the invasive treatment group had a better prognosis and lower incidence of adverse events compared with the conservative treatment group. Advanced age, creatinine level and a higher Killip class were inversely correlated with whether to perform an invasive intervention, while the use of beta-receptor-blocking agents was a favourable factor for invasive treatment. Hypertension and a higher Killip class were risk factors for in-hospital death, while the use of beta-receptor-blocking agents and diuretics decreased the risk of in-hospital death. Conclusions An invasive treatment strategy was superior to a conservative treatment strategy in patients with STEMI aged ≥80 years.
Databáze: OpenAIRE