Nanodiamonds and gold nanoparticles to obtain a hybrid nanostructure with potential applications in biomedicine
| Autor: | Noralvis Fleitas-Salazar, Andrei Sarabia-Sainz, Seidy Pedroso-Santana, Raúl Riera, Araceli Angulo-Molina, Erika Silva-Campa, Martín Pedroza-Montero |
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| Rok vydání: | 2018 |
| Předmět: |
Nanostructure
Materials science Fluorophore Mechanical Engineering Bioengineering Nanotechnology 02 engineering and technology General Chemistry Conjugated system 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Fluorescence 0104 chemical sciences chemistry.chemical_compound chemistry Mechanics of Materials Colloidal gold General Materials Science Electrical and Electronic Engineering 0210 nano-technology |
| Zdroj: | Nanotechnology. 29(43) |
| ISSN: | 1361-6528 |
| Popis: | Using detonation nanodiamonds and fluorescent nitrogen-vacancy center nanodiamonds, linked to gold nanoparticles, we synthesized two hybrid nanostructures (HGDs) that were subsequently conjugated with a fluorophore. An amplification effect induced by the gold nanoparticles increased the emission spectrum of the fluorophore, maximizing the possibilities for imaging applications of these HGDs. The incubation of the nanostructures with HeLa cells produced no alteration of cell viability after 3 h and showed the presence of nanostructures in the cell cytoplasm at 24 h. These observations also indicate the potential biomedical use of the proposed HGDs. |
| Databáze: | OpenAIRE |
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