Multisite Detection of Tn 1549 -Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida

Autor: Shelby R. Simar, Truc T. Tran, Kirsten B. Rydell, Diana Panesso, German A. Contreras, Jose M. Munita, Renzo O. Cifuentes, Lilian M. Abbo, Pranoti Sahasrabhojane, An Q. Dinh, Dierdre B. Axell-House, Tor Savidge, Samuel A. Shelburne, Blake M. Hanson, Cesar A. Arias
Rok vydání: 2023
Předmět:
Zdroj: Antimicrob Agents Chemother
ISSN: 1098-6596
0066-4804
Popis: In the United States, vanB-mediated resistance in enterococci is rare. We characterized three sequence type (ST) 6, vancomycin-resistant Enterococcus faecalis isolates causing bacteremia in unique patients in spatiotemporally distinct settings. Isolates were recovered between 2018 and 2020 in two cities in the United States (Houston, TX; Miami, FL). The isolates harbored the vanB operon on a chromosomally located Tn1549 transposon, and epidemiological data suggested multiple introductions of the vanB gene cluster into ST6 E. faecalis.
Databáze: OpenAIRE