Vasoactive intestinal peptide (VIP) localization in the epididymis of two vertebrate species
| Autor: | Marina Prisco, Luigi Rosati, Piero Andreuccetti |
|---|---|
| Přispěvatelé: | Rosati, L., Andreuccetti, P., Prisco, M. |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Period (gene) Vasoactive intestinal peptide Connective tissue General Biochemistry Genetics and Molecular Biology VIP receptor 03 medical and health sciences biology.animal Internal medicine Testis medicine Animals Receptor Spermatogenesis Epididymis General Immunology and Microbiology biology Reproduction Podarcis Vertebrate Lizards General Medicine biology.organism_classification Rats VIP stomatognathic diseases 030104 developmental biology medicine.anatomical_structure Endocrinology Vertebrates Epididymi General Agricultural and Biological Sciences hormones hormone substitutes and hormone antagonists Vasoactive Intestinal Peptide |
| Popis: | VIP and its receptors (VPACRs) are largely investigated in vertebrate testis, as well as their functions in the control of spermatogenesis and steroidogenesis. By contrast, a few data are available about the presence and role of VIP in the epididymis. The aim of the present paper was to investigate the localization of VIP and its receptors in the epididymis of two vertebrates: Podarcis sicula, a seasonal reproducer, and Rattus rattus, a continuous reproducer. By immunohystochemical investigation, we demonstrated for the first time that VIP and its receptors are widely represented in the epididymis of Podarcis sand Rattus; in particular in Podarcis, we showed that during the reproductive period, as well as in Rattus, VIP and its receptors are well represented in all the epithelial cells and the connective tissue of the epididymis; by contrast, during the non-reproductive period, VIP and its receptors are represented only in the connective tissue. The possible role of the VIP/VPACR system in the control of reproduction is discussed. |
| Databáze: | OpenAIRE |
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