Predictors of Increased Left Ventricular Filling Pressure in Dialysis Patients with Preserved Left Ventricular Ejection Fraction
| Autor: | Gani Bajraktari, Ali Hajdari, Lavdim Ibraimi, Ymer Elezi, Mimoza Berbatovci-Ukimeraj, Irfan Daullxhiu, Gjin Ndrepepa |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Heart Ventricles medicine.medical_treatment Diastole Doppler echocardiography Ventricular Function Left Renal Dialysis Internal medicine Ventricular Pressure medicine Humans Dialysis Heart Failure Ejection fraction medicine.diagnostic_test business.industry Age Factors Stroke Volume General Medicine Odds ratio Stroke volume Middle Aged Clinical Science Prognosis medicine.disease Echocardiography Heart failure Cardiology Ventricular pressure Kidney Failure Chronic Female Arterial hypertension Left ventricular systolic function business |
| Zdroj: | Croatian Medical Journal Volume 50 Issue 6 |
| ISSN: | 1332-8166 0353-9504 |
| DOI: | 10.3325/cmj.2009.50.543 |
| Popis: | Aim To study the left and right ventricular function and to assess the predictors of increased left ventricular (LV) fill ing pressure in dialysis patients with preserved LV ejection fraction. Methods This study included 63 consecutive patients (age 57 ± 14 years, 57% women) with end-stage renal failure. Echocardiography, including tissue Doppler measurements, was performed in all patients. Based on the median value of the ratio of transmitral early diastolic velocity to early myocardial velocity (E/E’ ratio), patients were divided into 2 groups: the group with high filling pressure (E/E’>10.16) and the group with low filling pressure (E/ E’≤10.16). Results Compared with patients with low filling pres sure, the group of patients with high filling pressure in cluded a higher proportion of diabetic patients (41% vs 13%, P = 0.022) and had greater LV mass index (211 ± 77 vs 172 ± 71 g/m 3 , P = 0.04), lower LV lateral long axis amplitude (1.4 ± 0.3 vs 1.6 ± 0.3 cm, P = 0.01), lower E wave (84 ± 19 vs 64 ± 18cm/s, P < 0.001), lower systolic myocardial velocity (S’: 8.6 ± 1. 5 vs 7.0 ± 1.3 cm/s, P < 0.001), and lower diastolic myocardial velocities (E’: 6.3 ± 1.9 vs 9.5 ± 2.9 cm/s, P < 0.001; A’: 8.4 ± 1.9 vs 9.7 ± 2.5 cm/s, P = 0.018). Multivariate analysis identified LV systolic myocardial velocity – S’ wave (adjusted odds ratio, 1.909; 95% confidence in terval, 1.060-3.439; P = 0.031) and age (1.053; 1.001-1.108; P = 0.048) as the only independent predictors of high LV filling pressure in dialysis patients. Conclusions In dialysis patients with preserved left ventricular ejection fraction, reduced systolic myocardial velocity and elderly age are independent predictors of increased left ventricular filling pressure. |
| Databáze: | OpenAIRE |
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