Lymphangioma-like Kaposi sarcoma: case report
| Autor: | Celia Posada García, A. García-Cruz, Carlos de la Torre, Ignacio García-Doval, Manuel Cruces |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty Skin Neoplasms medicine.medical_treatment Cryotherapy Dermatology Histogenesis Diagnosis Differential HIV Seronegativity Lymphangioma Biopsy medicine Humans Sarcoma Kaposi Aged Leg Classic Kaposi Sarcoma medicine.diagnostic_test Vascular disease business.industry General Medicine medicine.disease Combined Modality Therapy Herpesvirus 8 Human Female Sarcoma Differential diagnosis business |
| Zdroj: | Scopus-Elsevier García, Celia Posada; García-Cruz, Aranzazu; García-Doval, Ignacio; Torre, Carlos De La; & Cruces, Manuel José. (2009). Lymphangioma-like Kaposi sarcoma: Case report. Dermatology Online Journal, 15(9). Retrieved from: http://www.escholarship.org/uc/item/6193n4xk |
| ISSN: | 1087-2108 |
| Popis: | Kaposi sarcoma (KS) is a multifocal vascular disease with uncertain histogenesis. It is characterized by clinical and histologic polymorphism. The "lymphangioma-like" variant is very uncommon, accounting for less than 5% of all cases. We report the case of a 76-year-old woman, HIV negative, with a 4-year history of classic Kaposi sarcoma treated with cryotherapy who developed new bullous lesions on her lower extremities. Biopsy revealed histologic findings of lymphangioma-like KS (LLKS), together with areas of classic KS; HHV-8 staining was positive. Diagnosis of LLKS was made and the patient was proposed for radiotherapy. The lymphangioma-like Kaposi sarcoma is a rare morphologic expression of KS characterized by dilated and bizarrely shaped vascular channels lined by flattened endothelium permeating the dermis. "Bulla-like" lesions have been considered as a clinical hallmark of this variant. Its histologic appearance suggests a lymphatic origin of KS and it may resemble other vascular tumors. Findings of areas of typical KS and positive staining for HHV-8 may help to make a definitive diagnosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|