Greater intravenous fluid volumes are associated with prolonged recovery after colorectal surgery: a retrospective cohort study
| Autor: | M. Machina, Stuart A. McCluskey, Z Aga |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Blood Loss Surgical Plasma Substitutes Preoperative care Perioperative Care Cohort Studies 03 medical and health sciences 0302 clinical medicine Postoperative Complications 030202 anesthesiology Interquartile range Risk Factors medicine Humans 030212 general & internal medicine Aged Retrospective Studies Aged 80 and over Univariate analysis business.industry Age Factors Retrospective cohort study Odds ratio Perioperative Crystalloid Solutions Length of Stay Middle Aged Colorectal surgery Surgery Anesthesiology and Pain Medicine Anesthesia Anesthesia Recovery Period Fluid Therapy Female Isotonic Solutions business Colorectal Surgery Cohort study |
| Zdroj: | British journal of anaesthesia. 116(6) |
| ISSN: | 1471-6771 |
| Popis: | We carried out a retrospective assessment of whether perioperative fluid volume was associated with length of hospital stay (LOS) after colorectal surgery.A single-centre chart review was conducted on colorectal surgeries that took place between January 2008 and December 2013. The primary outcome was LOS, with prolonged LOS defined as greater than median LOS. Secondary outcomes included postoperative pulmonary oedema, acute renal failure, myocardial infarction, and mortality. Univariate analysis, multivariable logistic regression, and quantile regression analyses were conducted to examine the association between perioperative fluid volume and prolonged LOS.Of the 1242 procedures, 57% were elective, 62% oncological, and 31% laparoscopic. The median LOS was 8.2 days (interquartile range 5.2, 14.7). Patients received 3.2 (sd 1.5) litres of fluid in the perioperative period (operating and recovery rooms), predominantly crystalloid. The volume (in litres) of perioperative fluid was independently associated with prolonged LOS (odds ratio 1.23, 95% confidence interval 1.10-1.36, P0.01). This association persisted across the spectrum of definitions for prolonged LOS (10th-90th percentile). Logistic regression analysis also revealed that prolonged LOS was associated with age65 yr, Charlson Co-morbidity Index ≥3, use of colloids, emergent surgery, estimated blood loss200 ml, preoperative anaemia, erythrocyte transfusion, open surgeries, and surgical duration4 h (C-statistic=0.79, Hosmer-Lemeshow=0.36).Greater perioperative fluid volume was independently associated with prolonged duration of recovery across a spectrum of surgical risk profiles. Fluid restriction should be considered a part of the care package in enhanced recovery after surgery programmes for colorectal surgery. |
| Databáze: | OpenAIRE |
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