Involvement of the cell wall ofNocardia restricta on the bioconversions of steroid sapogenins

Autor:	T Kastelic-Suhadolc, I Belič
Rok vydání:	1991
Předmět:	Chromatography Physiology Bioconversion Chemistry medicine.medical_treatment General Medicine Sapogenin Protoplast Applied Microbiology and Biotechnology Steroid Cell wall Biochemistry medicine Biotechnology
Zdroj:	World Journal of Microbiology and Biotechnology. 7:22-24
ISSN:	1573-0972 0959-3993
Popis:	The bioconversion of tigogenin, (25R)-5α-spirostan-3β-ol byNocardia restricta to (25R)-4-spirosten-3-one and (25R)-1,4-spirostadien-3-one was strongly increased using protoplasts instead of intact cells. The same effect could be achieved by addingβ-cyclodextrin to the medium. Since 5β-steroid sapogenins pass through the cell wall without hindrance, it can be concluded that the cell wall ofNocardia restricta is a rate-limiting factor only for 5α-isomers.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d6e755a6f6e491495cd13fec43d097 https://doi.org/10.1007/bf02310914 Zobrazit plný text záznamu Full text from SpringerLink