Non-Contact Photoacoustic Imaging Using a Commercial Heterodyne Interferometer
| Autor: | Xueding Wang, Cheng Wang, Ting Feng, Chao Tian, Shengchun Liu, Guan Xu, Qian Cheng, David E. Oliver |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Materials science
business.industry Wave propagation Bandwidth (signal processing) 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences Piezoelectricity Article 010309 optics Vibration Interferometry Optics Transducer 0103 physical sciences Medical imaging Electrical and Electronic Engineering 0210 nano-technology business Instrumentation Heterodyne interferometer |
| Popis: | Most current photoacoustic imaging (PAI) systems employ piezoelectric transducers to receive photoacoustic signals, which requires coupling medium to facilitate photoacoustic wave propagation and are not favored in many applications. Here, we report an all-optical non-contact PAI system based on a commercial heterodyne interferometer working at 1550 nm. The interferometer remotely detects ultrasound-induced surface vibration and does not involve any physical contact with the sample. The theoretically predicated and experimentally measured noise equivalent detection limits of the optical sensor are about 4.5 and 810 Pa over 1.2 MHz bandwidth. Using a raster-scan PAI system equipped with the non-contact design, stereotactic boundaries of an artificial tumor in a pig brain were accurately delineated. The non-contact design also enables the tomographic PAI of biological tissue samples in a non-invasive manner. The preliminary results and analyses reveal that the heterodyne interferometer-based non-contact PAI system holds good potential in biomedical imaging. |
| Databáze: | OpenAIRE |
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